Concentrating on Chromatography

David Oliva

Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!

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Concentrating on Chromatography

Episodes (54)

Mar 31st Episode 54: AQbD Explained: How Design of Experiments is Transforming Chromatography (LC-MS, Pharma & Biopharma)
Mar 23rd Episode 53: How GLP-1 Drugs Are Analyzed: Chromatography & Mass Spectrometry Explained #analyticalchemistry
Mar 16th Episode 52: Mass Spec Without Chromatography? How DART is Changing Clinical & Forensic Testing

Concentrating on Chromatography

Mar 31, 2026
34¼ minutes
32 MB

In this episode of Concentrating on Chromatography, David Oliva sits down with Amanda Guiraldelli Mahr to break down one of the most important (and often misunderstood) concepts in analytical chemistry: Analytical Quality by Design (AQbD).If you’ve ever relied on trial-and-error for method development—or wondered how top labs are using Design of Experiments (DOE), modeling, and AI to work smarter—this episode is for you.Amanda shares insights from her work across small molecules, peptides, proteins, and biopharmaceuticals, including her experience with LC-MS, metabolomics, impurity analysis, and oligonucleotide therapeutics.--- What You’ll Learn in This Episode:* What AQb...

Concentrating on Chromatography

Episode 54: AQbD Explained: How Design of Experiments is Transforming Chromatography (LC-MS, Pharma & Biopharma)

David Oliva

00:00 -34:19