The Sepsis Spectrum

Sepsis Alliance

Forget everything you ever read in a textbook when it comes to antimicrobial resistance (AMR) and sepsis complications – because they rarely play by the rules. They evolve, adapt, and strike before it’s too late. While classic symptoms like fever, tachycardia, and hypotension are well known, the real challenge lies in recognizing the unexpected to reduce your mental list of those unknown, unknowns. Hosted by Critical Care RN & CNS Author Nicole Kupchik, The Sepsis Spectrum is an exploration of real-world patient cases, expert insights, and clinical deep dives to unravel the most complex presentations facing modern medicine. Through gripping stories and i...

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The Sepsis Spectrum

Episodes (17)

Dec 23, 2025 When Sepsis Hits the Lungs
Dec 16, 2025 What happens to the kidneys during sepsis?
Dec 9, 2025 Is the gut the real engine of sepsis?

The Sepsis Spectrum

Dec 23, 2025
47¼ minutes
0

Sepsis doesn’t just overwhelm the body, it can turn the lungs into ground zero for multi-organ dysfunction. In this episode, host Nicole Kupchik sits down with Dr. Julie Bastarache to explore how sepsis triggers Acute Respiratory Distress Syndrome (ARDS) in a significant portion of critically ill patients. Dr. Bastarache explains why sepsis-induced ARDS isn’t a single entity but a spectrum of clinical, physiologic and biologic responses, each requiring its own approach. From the fundamentals of mechanical ventilation and why low tidal volume remains lifesaving, to the emerging, and surprising protective effects of GLP-1 receptor agonists, Dr. Bastarache’s reve...

The Sepsis Spectrum

When Sepsis Hits the Lungs

Sepsis Alliance

00:00 -47:17