Sigma Nutrition Radio

Danny Lennon

Discussions about the science of nutrition, dietetics and health. The podcast that educates through nuanced conversations, exploring evidence and cultivating critical thinking. Hosted by Danny Lennon.

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Sigma Nutrition Radio

Episodes (615)

Yesterday #596: Why Do Omega-3 Trials Show Mixed Results?
Feb 24th #595: Neuroplasticity and Reducing Risk of Cognitive Impairment – Dr. Majid Fotuhi
Feb 17th How Much Dietary Fiber Do We Need to be Healthy? (SNP48)

Sigma Nutrition Radio

Mar 3, 2026
1¼ hours
63 MB

Omega-3 fatty acids (particularly EPA and DHA) have a long history in nutrition and cardiovascular medicine, yet the clinical trial literature is often perceived as inconsistent. This episode examines why some randomized trials show clear benefit while others show null or mixed findings, and how differences in trial design, dose, population risk, and outcome selection can materially change what we observe. A key theme is separating (1) the persistent cultural narratives around omega-3s (including origin stories that do not hold up well to modern evidence) from (2) the more precise, mechanistic and clinical questions about where supplemental EPA...

Sigma Nutrition Radio

#596: Why Do Omega-3 Trials Show Mixed Results?

Danny Lennon

00:00 -01:06:11